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Thawed hMSCs are similar in morphology to those that have never been frozen and then thawed. They may have elongated, slender processes or may be somewhat more compact 1 day after being seeded but, after readapting to culture, become identical to unfrozen cells. A variable number of cells fail to attach to the culture dish and remain as oating cells; these are removed in the course of routine medium changes. Some presumably donor-dependent variability in recovery from cryopreservation has been observed.

intelligence about enemy movements can then be relayed, in a proactive manner, to a remote base station. In fact, some routing protocols have been speci cally designed with military applications in mind [10]. Consider the case where a troop of soldiers needs to move through a battle eld. If the area is populated by a wireless sensor network, the soldiers can request the location of enemy tanks, vehicles, and personnel detected by the sensor network (Fig. 1.3). The sensor nodes that detect the presence of a tank can collaborate to determine its position and direction, and disseminate this information throughout the network. The soldiers can use this information to strategically position themselves to minimize any possible casualties. In chemical and biological warfare, close proximity to ground zero is needed for timely and accurate detection of the agents involved. Sensor networks deployed in friendly regions can be used as early-warning systems to raise an alert whenever the presence of toxic substances is detected. Deployment in an area attacked by chemical or biological weapons can provide detailed analysis, such as concentration levels of the agents involved, without the risk of human exposure. 1.3.2 Environmental Applications

to the molecular pharmacology of cancer. Science, 275, 343 349. Welch, W. J. (1982). Algorithmic complexity: Three NP-hard problems in computational statistics. Journal of Statistical Computation and Simulation, 15, 17 25. Wolfe, J. H. (1970). Pattern clustering by multivariate mixture analysis. Multivariate Behavioral Research, 5, 329 350. Wong, M. A. (1982). A hybrid clustering method for identifying high-density clusters. Journal of the American Statistical Association, 77, 841 847. Wong, M. A., & Lane, T. (1983). A kth nearest neighbour clustering procedure. Journal of the Royal Statistical Society, Series B, 45, 362 368. Zhang, T., Ramakrishnan, R., & Linvy, M. (1996). BIRCH: An ef cient data clustering method for very large databases. In Proceedings of the ACM SIGMOD Conference on the Management of Data (pp. 103 104). New York: Association for Computing Machinery.

However, in the context of the support vector learning, it is important that the clustering mechanism establishes groups within the data, assuring that these are also homogeneous with regard to the output variable Therefore, the vectors to which a clustering algorithm will be applied are obtained by augmenting the input samples with the desired output To modify the objective function used by the unsupervised clustering method, the augmented vector in Rn 1 : X x y is de ned As a result, the positions of the centers are in uenced not only by the input sample spread but also by the output values This will improve of the quality of the training data set (large data sets increase the training complexity and do not always make a better model accuracy or generalization).

Turnover ratios include the following: 1. Inventory turnover ratio 2. Inventory holding period: Cost of sales for the period Average inventory for the period Operating days in the period Inventory turnover ratio for the period Sales revenue Average working capital

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concentration is varied during the lm deposition process to provide a position-dependent SiGe alloy lm for pro le and device optimization of the SiGe HBT base region The epitaxial base region forms a single-crystal SiGe intrinsic base and an amorphous polySiGe extrinsic base region A window is formed over the single-crystal intrinsic SiGe base region to form the n-type polysilicon emitter After hot process steps, the n dopants of the emitter diffuse into the SiGe intrinsic base region Interconnection to the emitter, base, and collector is de ned by a tungsten (W) local interconnect Interlevel dielectrics (ILD) lms, tungsten contacts, and aluminum interconnects are formed with the reactive ion etching (RIE) and chemical mechanical polishing (CMP) processes used in base CMOS technology In today s technologies, copper interconnects have replaced aluminum interconnect lms Figure 62 shows a cross sectional drawing of a silicon germanium HBT.